THYROTROPIN RELEASING HORMONE

Code
000.0000
Name
THYROTROPIN RELEASING HORMONE
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
TRH
CPT Codes
83519
Site
SBMF
Reference Test
45699
ATLAS Test Code

Specimen Information

Type

Special collection tube with TRH preservative (Call lab for supplies)

Volume

2.0 ml

Transport Info

Centrifuge and immediately transfer plasma to separate plastic tube
Frozen

Fasting Required?
False
Patient Instructions

Reference Range

See Report

Methodology

Radioimmunoassay

Clinical Significance

Potential marker for TRH-secreting tumors.

Thryotropin-releasing hormone (TRH) is a tripeptide produced in the hypothalamus, other central nervous sites, and the gastrointestinal tract, especially the pancreas. TRH stimulates TSH synthesis and release. Most circulating TRH, which is reapidly degraded, is probably derived from extra-hypothalmic tissues. Circulating TRH levels are increased in fetal and neonatal serum because of increased TRH production from fetal gut tissues and placenta and low levels of TRH-degrading activity in fetal blood. Plasma TRH levels have not been shown to be useful in diagnosis of any known thryroid condition.

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