TISSUE TRANSGLUTAMINASE IGA ANTIBODY

Code
900.5390
Name
TISSUE TRANSGLUTAMINASE IGA ANTIBODY
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
tTg IgA Ab; Native human tissue transglutaminase antibody; h-tTG Ab
CPT Codes
83516
Site
SBMF
Reference Test
28014
ATLAS Test Code

Specimen Information

Type

Gold, SST

Volume

0.5 ml

Transport Info

Refrigerated

Fasting Required?
False
Patient Instructions

Reference Range

0.0-7.0 U/mL

Methodology

Enzyme-Linked Immunosorbent Assay (ELISA)

Clinical Significance

Celiac disease is a life-long condition in which ingestion of gluten leads to chronic inflammation and damage of the small intestinal mucosa. Tissue transglutaminase has been identified as the major autoantigen in celiac disease. IgA antibodies against tTG are highly disease specific serological markers for celiac disease and dermatitis herpetiformis.

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