TOTAL PROTEIN,BODY FLUID

Code
000.0000
Name
TOTAL PROTEIN,BODY FLUID
Category
None
Department
Chemistry
Start Date
Expiration Date
Synonyms
TPBF
CPT Codes
Site
Main Lab
Reference Test
ATLAS Test Code

Specimen Information

Type

Pleural fluid, Pericardial fluid, Peritoneal fluid, Synovial fluid (Prefer fluid transferred to Gold, SST for transport, sterile container acceptable)

Volume

2.0 ml

Transport Info

Refrigerated
Transport ASAP

Fasting Required?
False
Patient Instructions

Reference Range

See Report

Methodology

Colorimetric

Clinical Significance

Evaluate effusions; diagnose transudate versus exudate.

Fluid protein levels are helpful in the differentiation of transudates from exudates. A transudate is an effusion of fluid caused by mechanical factors. These factors include congestive heart failure, hepatic cirrhosis, and the nephrotic syndrome. A fluid protein level less than 3 g/dL is indicative of a transudate. An exudate is an effusion of fluid caused by damage which includes infection (including TB), neoplasia, inflammation, SLE, and trauma involving the mesothelial lining of a cavity. A fluid protein level greater than 3 g/dL is indicative of an exudate. Serous fluids for laboratory examination are collected by needle aspiration from body cavities. These aspiration procedures could include thoracentesis (pleural), pericardiacentesis (pericardial), synovial (joint) fluid and paracentesis (peritoneal). Many pathologic conditions can cause a buildup (effusion) of serous fluids. Effusion of serous fluid can be placed into two general categories: transudates and exudates. A transudate disrupts the balance in the regulation of fluid filtration and reabsorption. An example is the changes in hydrostatic pressure created by congestive heart failure. Exudates are produced by conditions that directly involve the membranes of the particular cavity including infections and malignancies. Analysis of body fluid usually includes one or more of the following: cell count, differential, total protein, crystals, pH, specific gravity, glucose, albumin, amylase, sodium, potassium, chloride, LD, creatinine, urea nitrogen, uric acid, routine culture, and cytologic studies. Additional testing may include specialized microbiology cultures for AFB or fungus or testing for the presence of bilirubin. Only those tests that are ordered will be performed.

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