UREA NITROGEN,24 HR URINE

Code
500.1900
Name
UREA NITROGEN,24 HR URINE
Category
None
Department
Chemistry
Start Date
Expiration Date
Synonyms
UUN (Urine Urea Nitrogen)
CPT Codes
84540, 81050
Site
Main Lab
Reference Test
ATLAS Test Code

Specimen Information

Type

Urine, 24-Hour

Volume

10.0 ml

Transport Info

Room Temperature
2 day stability

Refrigerated
7 day stability

Frozen
1 month stability

Fasting Required?
False
Patient Instructions

No preservative

Reference Range

12-20 g/24hr

Methodology

Enzymatic Rate

Clinical Significance

Used in the diagnosis of certain renal and metabolic diseases.

The determination of urea is the most widely used test for the evaluation of kidney function. The test is frequently used in conjunction with the determination of creatinine for the differential diagnosis of prerenal hyperuremia (cardiac decompensation, water depletion, increased protein catabolism), renal hyperuremia (glomerulonephritis, chronic nephritis, polycistic kidney, nephrosclerosis, tubular necrosis) and postrenal hyperuremia (obstructions of the urinary tract).Urea is the final degradation product of protein and amino acid metabolism. In protein catabolism the proteins are broken down into amino acids and deaminated. The ammonia formed in this process is synthesized to urea in the liver. This is the most important catabolic pathway for eliminating excess nitrogen in the human body.

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