VARICELLA ZOSTER IGG AB
- Code
- 900.5490
- Name
- VARICELLA ZOSTER IGG AB
- Category
- None
- Department
- Send-Out
- Start Date
- Expiration Date
- Synonyms
- VZV IgG Antibody, Chicken Pox Virus IgG Antibody, Herpes zoster IgG Antibody, Human Herpesvirus 3 (HHV-3) IgG Antibody
- CPT Codes
- 86787
- Site
- SBMF
- Reference Test
- 28175
Specimen Information
- Type
Gold, SST
- Volume
1.0 ml
- Transport Info
Refrigerated
- Fasting Required?
- False
- Patient Instructions
- Reference Range
≤ 0.8 AI = Negative - No IgG antibodies specific to Varicella-zoster virus detected. Patient is presumed not to have had a previous exposure to Varicella-zoster virus through infection or vaccination
0.9-1.0 AI = Equivocal results; obtain an additional sample for re-testing.
≥ 1.1 AI = Positive - IgG antibody to Varicella-zoster virus detected. This may indicate that the patient was exposed to Varicella-zoster virus through infection or vaccination.AI = Antibody Index
This test is not intended to be diagnostic for infectious disease and should only be utilized to establish serological status of the patient to Varicella-zoster virus.
Positive results may be found in patients that have not been immunized. In these cases, the patient has a positive serological status to the infectious agent through natural exposure. False positive results may occur. Repeat testing or testing with a different device may be indicated in some settings, e.g., patients with low likelihood of prior infection or vaccination.
- Methodology
Multiplex Flow Immunoassay (MFI)
Clinical Significance
Diagnose clinical infections with varicella or herpes zoster
Assess immune status of individuals exposed to varicella, especially pregnant women
Varicella (i.e., chickenpox) is a highly contagious disease caused by Varicella-zoster virus (VZV). VZV causes a systemic infection that usually results in lifetime immunity. In otherwise healthy persons, clinical illness after re-exposure is rare. However, as with other viral diseases, re-exposure to wild-type VZV may lead to reinfection that boosts antibody titers without causing clinical illness or detectable viremia.