HEPATITIS DELTA VIRUS ANTIGEN
- HEPATITIS DELTA VIRUS ANTIGEN
- Start Date
- Expiration Date
- HDV Ag
- CPT Codes
- Reference Test
- ATLAS Test Code
- Transport Info
Centrifuge and immediately transfer serum to separate plastic tube
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
- Fasting Required?
- Patient Instructions
- Reference Range
Qualitative Enzyme-Linked Immunosorbent Assay (ELISA)
The Hepatitis Delta Virus (HDV) is a defective RNA virus, composed of a core presenting the delta-specific antigen and encapsulated by Hepatitis B surface antigen, which requires the helper function of Hepatitis B virus (HBV) to support its replication.
Infection by HDV occurs in the presence of acute or chronic HBV infection. When acute delta and acute HBV simultaneously occur, the illness becomes severe and clinical and biochemical features may be indistinguishable from those of HBV infection alone. In contrast, a patient with chronic HBV infection can support HDV replication indefinitely, usually with a less severe illness appearing as a clinical exacerbation.
The determination of HDV specific serological markers represents, in these cases, an important tool to the clinician for the classification of the etiological agent, and follow up of infected patients and monitoring their treatment. The detection of HDV IgM and IgG antibodies allows the classification of the illness and the monitoring of the seroconversion event. The Hepatitis D antigen test is intended for the follow-up of HDV infected individuals.