BILIRUBIN NEONATAL PROFILE

Code
400.3480
Name
BILIRUBIN NEONATAL PROFILE
Category
None
Department
Chemistry
Start Date
Expiration Date
Synonyms
CPT Codes
Site
Main Lab
Reference Test
ATLAS Test Code

BIL NP

Specimen Information

Type

Gold, SST, Protect from light

Volume

1.0 ml

Transport Info

Refrigerated 24 hour stability

Fasting Required?
False
Patient Instructions

Test includes: Total, Direct, and Indirect Neonatal Bilirubin

Reference Range

See Report

Methodology

Timed endpoint

Clinical Significance

Monitor erythroblastosis fetalis, hemolytic disease of the newborn, other causes of neonatal jaundice. In obstructive jaundice, there is an increase in the total bilirubin, but the increase is primarily in the bilirubin glucuronide. In hemolytic jaundice and in neonatal jaundice, there is an increase primarily in the indirect (the difference between total and direct) bilirubin. In newborns, the jaundice may be caused by Rh, ABO or other blood group incompatibilities, by hepatic immaturity or by hereditary defects in bilirubin conjugation. Both direct and indirect bilirubin are increased in hepatitis. The relative proportion of the direct fraction increases with progression of the disease until eventually the liver loses its ability to carry out the conjugation reaction.

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