ACETAMINOPHEN (TYLENOL)

Code
600.4900
Name
ACETAMINOPHEN (TYLENOL)
Category
None
Department
Chemistry
Start Date
Expiration Date
Synonyms
Tylenol
CPT Codes
82003
Site
Main Lab
Reference Test
ATLAS Test Code

ACET

Specimen Information

Type

Gold, SST

Volume

1.0 ml

Transport Info

Refrigerated 48 hour stability Frozen 1 month stability

Fasting Required?
False
Patient Instructions

Reference Range

10-25 ug/mL <300 ug/mL @ 4 hrs <50 ug/mL @12 hrs

Methodology

Turbidimetric

Clinical Significance

Acetaminophen, a commonly used analgesic drug, may cause severe hepatic toxicity or death when consumed in overdose quantities. The initial clinical findings in acetaminophen toxicity are relatively mild and non-specific and are therefore not predictive of impending hepatic necrosis, which typically is not evident until three to five days after ingestion. For this reason, the measurement of serum acetaminophen concentration becomes paramount for proper assessment of the severity of overdose and for making appropriate therapeutic decisions. In most cases the analysis of serum acetaminophen following suspected overdose would be made at least four hours after the last acetaminophen ingestion. This is to ensure that peak levels have been achieved.

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