BORRELIA BURGDORFERI AB, TOTAL BY ELISA, CSF

Code
000.0000
Name
BORRELIA BURGDORFERI AB, TOTAL BY ELISA, CSF
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
Lyme Disease Antibodies; Total; by ELISA; CSF
CPT Codes
86618
Site
SBMF
Reference Test
44143
ATLAS Test Code

Specimen Information

Type

CSF

Volume

3.0 ml

Transport Info

Refrigerated

Fasting Required?
False
Patient Instructions

Reference Range

0.99 LIV or less: Negative - Antibody to Borrelia burgdorferi not detected.
1.00-1.20 LIV: Equivocal - Repeat testing in 10-14 days may be helpful.
1.21 LIV or greater: Positive - Probable presence of antibody to Borrelia burgdorferi detected.

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)

Clinical Significance

Current CDC recommendations for the serologic diagnosis of Lyme Disease are to screen with a polyvalent EIA test and confirm equivocal and positive results with Western Blot. Both IgM and IgG Western Blots should be performed on samples less than 8 weeks after appearance of erythema migrans. Only IgG Western Blot should be performed on samples greater than 8 weeks after the disease onset. IgM Western Blot in the chronic stage is not recommended and does not aid in the diagnosis of neuroborreliosis or chronic Lyme disease. Please submit requests for appropriate Western Blot testing within 10 days. Note: Once this test is performed, if: a) Negative - no further testing is done b) Positive or equivocal - Western blot testing will be performed on the original sample upon receiving a request; sample will be held for 30 days only.

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