NABFERON (IFN-B) ANTIBODY TEST

Code
000.0000
Name
NABFERON (IFN-B) ANTIBODY TEST
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
IFN-B Ab
CPT Codes
86352; If indicated, add 86352
Site
SBMF
Reference Test
45783
ATLAS Test Code

Specimen Information

Type

Gold, SST

Volume

1.0 ml

Transport Info

Centrifuge and immediately transfer serum to separate plastic tube
Refrigerated

Fasting Required?
False
Patient Instructions

Collect specimens before Interferon beta treatment, or more than 48 hours following the most recent dose. Patient should not be on steroid therapy in excess of 10 mg prednisolone (or equivalent) daily. High endogenous levels of Interferon beta, alpha, or gamma may interfere with this assay.

Reference Range

Interferon Beta Screen
Negative

Interferon Beta Titer
Less than 20: Negative
20 to 99: Moderate levels of neutralizing antibodies present
100 or greater: High levels of neutralizing antibodies present

Methodology

Cell Culture
Chemiluminescent Immunoassay (CLIA)

Clinical Significance

Detection of antibodies to interferon-ß-1.

Type of Disorder: Multiple Sclerosis. Typical Presentation: Individuals on interferon-ß1 therapy with suspected exacerbations and/or lack of response to therapy.

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