NABFERON (IFN-B) ANTIBODY TEST
- Code
- 000.0000
- Name
- NABFERON (IFN-B) ANTIBODY TEST
- Category
- None
- Department
- Send-Out
- Start Date
- Expiration Date
- Synonyms
- IFN-B Ab
- CPT Codes
- 86352; If indicated, add 86352
- Site
- SBMF
- Reference Test
- 45783
Specimen Information
- Type
Gold, SST
- Volume
1.0 ml
- Transport Info
Centrifuge and immediately transfer serum to separate plastic tube
Refrigerated- Fasting Required?
- False
- Patient Instructions
Collect specimens before Interferon beta treatment, or more than 48 hours following the most recent dose. Patient should not be on steroid therapy in excess of 10 mg prednisolone (or equivalent) daily. High endogenous levels of Interferon beta, alpha, or gamma may interfere with this assay.
- Reference Range
Interferon Beta Screen
NegativeInterferon Beta Titer
Less than 20: Negative
20 to 99: Moderate levels of neutralizing antibodies present
100 or greater: High levels of neutralizing antibodies present- Methodology
Cell Culture
Chemiluminescent Immunoassay (CLIA)
Clinical Significance
Detection of antibodies to interferon-ß-1.
Type of Disorder: Multiple Sclerosis. Typical Presentation: Individuals on interferon-ß1 therapy with suspected exacerbations and/or lack of response to therapy.