CARNITINE, FREE & TOTAL (INCLUDES CARNITINE, ESTERIFIED)
- CARNITINE, FREE & TOTAL (INCLUDES CARNITINE, ESTERIFIED)
- Start Date
- Expiration Date
- L-carnitine Free & Total
- CPT Codes
- Reference Test
Green top (heparin) tube
- Transport Info
Centrifuge and mmediately transfer plasma to separate plastic tube
CRITICAL FROZEN – Separate samples must be submitted when multiple tests are ordered
- Fasting Required?
- Patient Instructions
Form required: "Patient History for Biochemical Genetic Testing"
- Reference Range
Tandem Mass Spectrometry (MS/MS)
Carnitine functions to transport long-chain fatty acids into mitochondria as a part of oxidative phosphorylation.
Carnitine functions to transport long-chain fatty acids into mitochondria as a part of oxidative phosphorylation. Synthesis by liver, kidney, and brain accounts for about 1/3 of daily needs with diet providing the rest. Associated lipid storage myopathies identified to date include: Carnitine deficiency (type I lipid storage myopathy). Carnitine-palmityltransferase (CPT) deficiency. Pyruvate-decarboxylase deficiency. Carnitine deficiency has been suggested as the primary cause of human lipid storage myopathy. Deficiencies have also been reported in premature infants and in patients with cirrhosis, renal failure, and long-term nutritional therapy (TPN). Serum carnitine levels increase during attacks of myoglobinuria.