CAROTENE

Code
900.0850
Name
CAROTENE
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
Provitamin A
CPT Codes
82380
Site
SBMF
Reference Test
47119
ATLAS Test Code

Specimen Information

Type

Gold, SST, protected from light

Volume

2.0 ml

Transport Info

Centrifuge and immediately transfer serum to light-protected (amber) plastic tube
Frozen

If light-protected tube unavailable, wrap the specimen in foil

Fasting Required?
False
Patient Instructions

Wrap tube in foil to protect sample from light exposure
Do not place specimen label over foil wrap

Reference Range

50-250 µg/dL

Methodology

Spectrophotometry

Clinical Significance

Useful as a screening method for the detection of malabsorption of fat.

Carotene or provitamin A determination in serum is the most useful single screening method for the detection of malabsorption of fat. Carotene is a fat-soluble pigment that is slowly absorbed. It is found in leafy vegetables, fruits, and liver. The absorption of carotene requires the presence of dietary lipids; limited amounts of these lipids are stored in the liver. When malabsorption of fats occurs, serum carotene is greatly decreased.Carotene levels are lowest in primary malabsorption. Levels may also be low in enteritis and many diseases associated with steatorrhea. High fever, hepatic disease, and deficient diet may also cause low carotene levels.Carotene values are increased in diabetes, hyperlipemia, carotenemia, and hypothyroidism.

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