CATECHOLAMINES 24HR URINE

Code
900.0910
Name
CATECHOLAMINES 24HR URINE
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
Fractionated 24- hour Catecholamines; adrenaline; urine epinephrine
CPT Codes
82384
Site
SBMF
Reference Test
29130
ATLAS Test Code

Specimen Information

Type

Urine, 24-Hour

Volume

10.0 ml

Transport Info

Refrigerated

Fasting Required?
False
Patient Instructions

Reference Range

See report

Methodology

High Performance Liquid Chromatography (HPLC)

Clinical Significance

Elevations in urinary catecholamines may be an indication of a pheochromocytoma or neuroblastoma, progressive muscular dystrophy, or myasthenia gravis. A decrease may be observed in familial dysautomia, malnutrition, or transection of cervical spinal cord.

Pheochromocytoma, a tumor of the chromaffin tissue, is associated with the presence of great increased catecholamine concentrations. Elevated catecholamines have also been found in patients with other tumors of neural tube origin, such as neuroblastomas and ganglioneuroblastomas. Degradation products of catecholamines, normetanephrine, metanephrine, and vanilmandelic acid (VMA) may be measured in conjunction with the catecholamines. These compounds are present in the urine in much larger quantities than epinephrine, norepinephrine, or dopamine.

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