CERULOPLASMIN

Code
900.1000
Name
CERULOPLASMIN
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
CPT Codes
82390
Site
SBMF
Reference Test
28165
ATLAS Test Code

CERU

Specimen Information

Type

Gold, SST

Volume

1.0 ml

Transport Info

Refrigerated

Fasting Required?
False
Patient Instructions

Reference Range

20-60 mg/dL

Methodology

Quantitative Nephelometry

Clinical Significance

Aid in the diagnosis of copper metabolism disorders; support the diagnosis of Wilson's disease; evaluate cirrhosis, liver disease, and central nervous system disease of obscure etiology; and neurological symptoms reflecting lesions of the lenticular nuclei. Cerulopasmin is the main transport protein for copper in the blood. In addition, the protein exhibits enzymatic activity as an oxidase for various substrates. In Wilson’s disease and Menke’s syndrome (hereditary disorders of copper metabolism), the serum ceruloplasmin levels are markedly diminished, especially in homozygotes. Low levels of ceruloplasmin also occur in patients with hepatic insufficiency and protein loss syndrome. High serum levels of ceruloplasmin are observed in acute-phase reactions, during use of oral contraceptives and with cholestase.

Back

Patients & Visitors

Make a First Appointment Maternity Pre-Registration Make a Donation Recognize a Sarah Bush Lincoln Employee