ALKALINE PHOSPHATASE
- Code
- 400.4000
- Name
- ALKALINE PHOSPHATASE
- Category
- None
- Department
- Chemistry
- Start Date
- Expiration Date
- Synonyms
- Alk Phos; ALP
- CPT Codes
- 84075
- Site
- Main Lab
- Reference Test
Specimen Information
- Type
Gold, SST
- Volume
1.0 ml
- Transport Info
Refrigerated
48 hour stability- Fasting Required?
- False
- Patient Instructions
- Reference Range
30-105 IU/L
- Methodology
Colorimetric
Clinical Significance
Diagnosis and treatment of liver, bone, parathyroid and intestinal diseases.
Determinations of alkaline phosphatase (ALP) are important in liver and bone disorders. Levels of ALP are increased in both extrahepatic and intrahepatic obstructive disease and cirrhosis. Other liver abnormalities such as hepatic tumors, hepatotoxic drugs, and hepatitis cause lesser elevation in ALP levels. Pathologic new bone growth occurs with osteoblastic metastatic (e.g. breast, prostate) tumors with bone being the most frequent extrahepatic source of ALP. If ALP is the only raised value within a liver function panel, it should not be assumed that it is of hepatic origin. Additional testing should be done to rule out an extrahepatic source.