EHRLICHIA CHAFFEENSIS IGM ANTIBODY BY IFA

Code
000.0000
Name
EHRLICHIA CHAFFEENSIS IGM ANTIBODY BY IFA
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
Human Monocytic Ehrlichiosis IgM Antibody, HME IgM Antibody
CPT Codes
86666
Site
SBMF
Reference Test
44329
ATLAS Test Code

Specimen Information

Type

Gold, SST

Volume

1.0 ml

Transport Info

Centrifuge and immediately transfer serum to separate plastic tube
Refrigerated

Fasting Required?
False
Patient Instructions

Reference Range

< 1:16 Negative-No significant level of Ehrlichia chaffeensis IgM antibody detected.
≥ 1:16 Positive-Presence of IgM antibody to Ehrlichia chaffeensis detected, suggestive of current or recent infection.

Methodology

Semi-Quantitative Indirect Fluorescent Antibody (IFA)

Clinical Significance

While the presence of IgM antibodies suggests current or recent infection, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection. A single IgM result should be interpreted with caution.

Note:
Human ehrlichiosis is a tick-borne disease caused by rickettsial-like agents. Two forms, human monocytic ehrlichiosis (HME) and human granulocytic ehrlichiosis (HGE), have been described. HME is often referred to as "spotless" or rashless Rocky Mountain spotted fever, and has been reported in various regions of the United States. The causative agent of HME has been identified as Ehrlichia chaffeensis. Infected individuals produce specific antibodies to Ehrlichia chaffeensis which can be detected by an immunofluorescent antibody (IFA) test.

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