ERYTHROCYTE SEDIMENTATION RATE

Code
100.6400
Name
ERYTHROCYTE SEDIMENTATION RATE
Category
None
Department
Hematology
Start Date
Expiration Date
Synonyms
ESR; Sed Rate; Sedimentation Rate
CPT Codes
85652
Site
Main Lab
Reference Test
ATLAS Test Code

Specimen Information

Type

Lavender, EDTA

Volume

2.0 ml

Transport Info

Refrigerated
24 hour stability
4 hour stability @ room temperature

Fasting Required?
False
Patient Instructions

Reference Range

See report

Methodology

Westergren

Clinical Significance

The sedimentation rate is used as a screening test for the presence of infection and to diagnose and to monitor the progress of chronic inflammatory processes such as rheumatoid arthritis, temporal arteritis or polymyalgia rheumatica.

The Erythrocyte Sedimentation Rate (ESR) is often used as an indirect measure of temporal arteritis activity as well as to help guide dosage adjustments and corticosteroids. The ESR is valuable in identifying patients with active temporal arteritis and those experiencing a recurrence. There is, however, no correlation between the elevation of the ESR and the severity of the disease. Temporal arteritis in an autoimmune disease of the elderly causing a chronic inflammation of the branches of the aortic arch that can lead to blindness or stroke. The ESR is believed to depend primarily, but not exclusively, on the concentration of asymmetric macro-molecules, primarily fibrinogen and gamma globulin, and on the concentration of erythrocytes in plasma. Because the concentrations of fibrinogen or gamma globulin, or both, are commonly elevated in inflammatory disease, the sedimentation rate is used as a screening test for the presence of infection and to diagnose and to monitor the progress of chronic inflammatory processes such as rheumatoid arthritis, temporal arteritis or polymyalgia rheumatica.

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