ESTROGEN/PROGESTERONE RECEPTOR ASSAY, PARAFFIN BLOCK
- ESTROGEN/PROGESTERONE RECEPTOR ASSAY, PARAFFIN BLOCK
- Start Date
- Expiration Date
- CPT Codes
- Reference Test
- ATLAS Test Code
Paraffin block containing embedded tissue
- Transport Info
- Fasting Required?
- Patient Instructions
- Reference Range
Estrogen and progesterone receptors by immunohistochemistry are reported as: positive (with 15% to greater than 90% nuclear positivity), weakly positive (with 5% to 10% nuclear positivity), and negative (with 0% to less than 5%) nuclear positivity.
A useful biochemical parameter in deciding which patients with breast cancer should be treated by endocrine therapy such as androgens, tamoxifen, or adrenalectomy.
The hormone receptor assays lend predictive value to the patient's response to endocrine therapy. Evidence exists that the incidence of response is enhanced when progesterone receptor is also present. Meningiomas frequently contain progesterone receptors. Such assays are sometimes useful for female patients with metastatic adenocarcinoma of unknown primary site.