ENA PANEL

Code
900.1480
Name
ENA PANEL
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
Mixed Connectivce Tissue Disease Panel, Extractable Nuclear Antigen (ENA) Antibodies, Anti-RNP Antibody, Smith Ab
CPT Codes
86235x3
Site
SBMF
Reference Test
28347
ATLAS Test Code

Specimen Information

Type

Gold, SST

Volume

1.0 ml

Transport Info

Refrigerated

Fasting Required?
False
Patient Instructions

Reference Range

See report

Methodology

Multiplex Flow Immunoassay

Clinical Significance

Anti-Sm is generally diagnostic for systemic lupus erythematosus (SLE)

Anti-RNP is mainly seen in mixed connective tissue disease (MCTD).

While anti-nuclear antibody (ANA) tests are employed for initial screening, follow-up tests for ANA-positive samples are needed to identify specific antibodies to nuclear antigens such as DNA, histones, and saline-extractable nuclear antigens. Current trends in immunopathology indicate that a detailed analysis of antibody specificities is useful in establishing the correct diagnosis and prognosis.

Back