GABAPENTIN LEVEL (NEURONTIN)

Code
900.2850
Name
GABAPENTIN LEVEL (NEURONTIN)
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
NEURONTIN
CPT Codes
80299
Site
SBMF
Reference Test
44567
ATLAS Test Code

Specimen Information

Type

Red, Plain

Volume

1 ml

Transport Info

Centrifuge and immediately transfer serum to separate plastic tube
Refrigerated

Fasting Required?
False
Patient Instructions

Reference Range

An exact therapeutic range has not been established - Minimum concentration of 2.0 µg/mL is desirable for efficacy - Majority of patients at suggested doses fall within a 2.0-10.0 µg/mL range - No critical value has been determined

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Clinical Significance

The proposed therapeutic range for seizure control is 2-10 µg/mL. Concentrations that exceed 25 µg/mL may contribute to adverse effects. Pharmacokinetics of gabapentin varies widely among patients, particularly those with compromised renal function.

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