HELICOBACTER PYLORI RAPID UREASE TEST, MUCOSAL BIOPSY
- Code
- 000.0000
- Name
- HELICOBACTER PYLORI RAPID UREASE TEST, MUCOSAL BIOPSY
- Category
- None
- Department
- Histology
- Start Date
- Expiration Date
- Synonyms
- H. pylori, Urease, Tissue; RUT; CLO Test
- CPT Codes
- 87081
- Site
- SBMF
- Reference Test
- 21040
Specimen Information
- Type
Selective Rapid Urea media
- Volume
3 mm diameter
- Transport Info
Room Temperature
- Fasting Required?
- False
- Patient Instructions
- Reference Range
Negative for H. pylori
- Methodology
Rapid Urease
Clinical Significance
Detect presence of H. pylori in tissue sample.
Helicobacter pylori has been shown to cause active chronic gastritis and has been implicated as a primary etiological factor in duodenal ulcer disease, gastric ulcer, and non-ulcer dyspepsia. By causing chronic inflammation, H. pylori may weaken the mucosal defenses and allow acid and pepsin to disrupt the epithelium. H. pylori produces large amounts of urease enzyme. Although H. pylori can be detected with histology or culture of gastric tissue, simple tests for the presence of urease enables more rapid and convenient diagnosis.