- Start Date
- Expiration Date
- CPT Codes
- Reference Test
*IF NEEDED STAT, PLEASE CONTACT LAB BEFORE DRAWING PATIENT*
- Transport Info
Centrifuge and immediately transfer plasma to separate plastic tube
CRITICAL FROZEN – Separate specimens must be submitted when multiple tests are ordered
- Fasting Required?
- Patient Instructions
Tube must be at least 3/4 full. After collection, immediately place tube in ice slush (ice and water mixture). Deliver tube to laboratory within 30 minutes of collection time for centrifugation. Plasma must be removed from cells within 30 minutes of collection time
- Reference Range
Critical High: 70 µmol/L or greater
Useful in the diagnosis and prognosis of Reye’s syndrome.
The bulk of ammonia in the body is generated in the gastrointestinal system by action of bacterial enzymes on the contents of the colon and from hydrolysis of glutamine. It is removed in the liver and converted to urea through a series of enzymatic reactions in the Krebs-Henseleit cycle. Among other conditions, advanced liver disease and hepatic encephalopathy result in elevated levels of ammonia in blood. The determination of ammonia is very useful in the diagnosis and prognosis of Reye’s syndrome. Elevated blood ammonia exerts toxic effects on the central nervous system.