HEPATITIS A IGG/IGM TOTAL AB

Code
900.1747
Name
HEPATITIS A IGG/IGM TOTAL AB
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
Anti-HAV; HAV Total Ab
CPT Codes
86708
Site
SBMF
Reference Test
28178
ATLAS Test Code

Specimen Information

Type

Gold, SST

Volume

1.0 ml

Transport Info

Refrigerated

Fasting Required?
False
Patient Instructions

Reference Range

Anti-HAV, total: Non-Reactive

Methodology

Chemiluminescent Immunoassay (CLIA)

Clinical Significance

Detect presence of total IgG/IgM HAV antibodies to diagnose either a current or recent HAV infection (IgM specific) or to diagnose a previous HAV infection (IgG specific); evaluate hepatitis.

The serologic diagnosis of acute hepatitis A virus (HAV) infection depends upon the demonstration of IgM-specific anti-HAV. This antibody usually appears about 4 weeks after infection and may persist for up to 4 months after the onset of clinical symptoms. The presence of IgG or total (IgM and IgG) antibody indicates past infection or immunization and associated immunity. The total assay detects both IgG and IgM antibodies, but does not differentiate between them. The Hepatitis A Antibody, IgM assay is appropriate when acute Hepatitis A infection is suspected. The FDA licensed an HAV vaccine in 1995.Total anti-HAV is useful in determining the immune status of a patient. It is especially useful for those patients recently diagnosed with HCV infection. These patients should receive HAV vaccination if anti-HAV is negative.IgM anti-HAV is useful in the work-up of suspected acute viral hepatitis.

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