HEPATITIS C ANTIBODY

Code
900.5815
Name
HEPATITIS C ANTIBODY
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
Anti-HCV; HCV Ab
CPT Codes
86803
Site
SBMF
Reference Test
28299
ATLAS Test Code

Specimen Information

Type

Gold, SST

Volume

1.0 ml

Transport Info

Specimen for HCV Ab test:
Room temperature serum: 4 days
Refrigerated serum: 21 days
Refrigerated plasma: 7 days
Frozen: 3 months (avoid repeated freeze/thaw cycles)

Fasting Required?
False
Patient Instructions

Reference Range

Negative

Methodology

Electrochemiluminescent Immunoassay (ECLIA)

Clinical Significance

Differential diagnosis of acute hepatitis and evaluation of post-transfusion hepatitis. All blood donor units are tested for HCV.

Hepatitis C Virus (HCV) is a positive-sense, single-stranded RNA virus of the Flaviviridae family. The viral genome contains approximately 10,000 nucleotides that code for 3,000 amino acids. HCV accounts for 20 percent of all cases of acute hepatitis. Chronic infection is responsible for an estimated 8,000 to 10,000 deaths per year. Infection with HCV is now the leading reason for liver transplantation in the United States. The virus is blood-borne and is transmitted primarily by the parenteral route. Infection with HCV may occur in individuals who have received transfusions of blood or blood products prior to 1990, those who are undergoing renal dialysis or have received organ transplants, and those who have a history of intravenous drug use or intranasal cocaine use.

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