IMMUNOGLOBULIN E

Code
700.0000
Name
IMMUNOGLOBULIN E
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
IGE, ALLERGEN, TOTAL IGE
CPT Codes
82785
Site
SBMF
Reference Test
30099
ATLAS Test Code

Specimen Information

Type

Gold, SST

Volume

1.0 ml

Transport Info

Refrigerated

Fasting Required?
False
Patient Instructions

Reference Range

See report

Methodology

ImmunoCAP™ Fluorescent Enzyme Immunoassay (FEIA)

Clinical Significance

Diagnose and manage patients with atopic disease such as asthma, hay fever, eczema, and patients with respiratory allergies or parasitic infections.

Immunoglobulin E (IgE) is a class of immunoglobulins important in the mediation of allergic responses. IgE is synthesized primarily within plasma cells found in the mucosa of the respiratory and intestinal tracts and is secreted into the blood. The mechanism of action of the allergic response involves the binding of IgE through its Fc portion to cell surface receptors of mast cells and basophils. After exposure to specific allergens recognized by IgE, the cells release vasoactive amines causing Type I hypersensitivity reactions. IgE levels may be increased in not only allergic disease, but also parasitic infections and bronchopulmonary aspergillosis.

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