LACTOSE TOLERANCE

Code
000.0000
Name
LACTOSE TOLERANCE
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
CPT Codes
82951; 82952 x 2
Site
SBMF
Reference Test
29010
ATLAS Test Code

Specimen Information

Type

Gold, SST

Volume

1.0 ml

Transport Info

Refrigerated

Fasting Required?
False
Patient Instructions

Adults: fasting at least 12 hours
Infants less than 2 years old: fasting 2 hours

Reference Range

An increase of 30 mg/dL over the fasting glucose level is considered normal
A rise of 20-30 mg/dL is inconclusive
An increase of less than 20 mg/dL is evidence for a deficiency of intestinal lactase

Methodology

Enzymatic

Clinical Significance

Detect the presence of normal or deficient lactase activity in the small intestinal mucosa.

The lactose tolerance test is used to detect the presence of normal or deficient lactase activity in the small intestinal mucosa. This enzyme splits lactose into galactose and glucose that can be absorbed into the blood.The fasting patient is given an oral dose of lactose. Serum specimens are analyzed for glucose before and at timed intervals after drinking the lactose. Glucose is measured by any of the standard glucose procedures.If normal lactase activity is present, the lactose will be hydrolyzed to glucose and galactose, and the serum glucose values will be similar to a glucose tolerance curve. With lactase deficiency the tolerance curve is flat with a rise not exceeding 20 mg/dL higher than the fasting level.

Back