LDH
- Code
- 400.4300
- Name
- LDH
- Category
- None
- Department
- Chemistry
- Start Date
- Expiration Date
- Synonyms
- CPT Codes
- 83615
- Site
- Main Lab
- Reference Test
Specimen Information
- Type
Gold, SST
- Volume
1.0 ml
- Transport Info
Refrigerated
- Fasting Required?
- False
- Patient Instructions
- Reference Range
80-180 IU/L
- Methodology
Enzymatic Rate
Clinical Significance
Elevations are found in cardiac disease including myocardial infarction, liver diseases including cirrhosis and alcoholism, neoplasia, infectious mononucleosis, hypothyroidism, lung diseases, diseases of central nervous system, infections, inflammatory states, hemolytic anemia, megaloblastic anemia including pernicious anemia, muscular damage, muscular dystrophy, collagen disease • High levels occur with renal infarct, without significant elevation of AST, ALT, or alkaline phosphatase.
LD is found in all cells of the body, with extremely high levels found in specific tissues such as the heart, liver, kidneys, skeletal muscle, and erythrocytes. Therefore, increased levels seen in the serum can be directly related to damage of one of these tissues. Tissue levels of LD are 500-fold higher than whole blood levels. Total LD can be used to differentiate myocardial infarction, in which total LD is three to four times normal, from angina and periocarditis, in which LD levels are normal.