MEPROBAMATE

Code
000.0000
Name
MEPROBAMATE
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
Equagesic, Equanil, Meprospan, Miltown, Neuramate
CPT Codes
83805
Site
SBMF
Reference Test
44962
ATLAS Test Code

Specimen Information

Type

Red, Plain

Volume

1.0 ml

Transport Info

Centrifuge and immediately transfer serum to separate plastic tube
Refrigerated

Fasting Required?
False
Patient Instructions

Reference Range

Therapeutic Range:
5-20 µg/mL
Toxic: > 40 µg/mL

Methodology

Gas Chromatography

Clinical Significance

Detect use. Evaluate therapeutic effect or possible toxicity.

Meprobamate (Equanil, Miltown) is the prototype of the medicinal carbamates, having been synthesized in 1950 and introduced in 1955 for clinical usage. It is employed as a sedative, antianxiety agent, and muscle relaxant and is available or oral administration in doses of 200-400 mg, alone or in combination with other drugs. As much as 2400 mg may be consumed in a single day. Side-effects of meprobamate usage include drowsiness, headache, dizziness, nausea, and paradoxical excitement. Several cases of severe hypotension and one case of fatal aplastic anemia have also been reported.

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