MEPROBAMATE
- Code
- 000.0000
- Name
- MEPROBAMATE
- Category
- None
- Department
- Send-Out
- Start Date
- Expiration Date
- Synonyms
- Equagesic, Equanil, Meprospan, Miltown, Neuramate
- CPT Codes
- 83805
- Site
- SBMF
- Reference Test
- 44962
Specimen Information
- Type
Red, Plain
- Volume
1.0 ml
- Transport Info
Centrifuge and immediately transfer serum to separate plastic tube
Refrigerated- Fasting Required?
- False
- Patient Instructions
- Reference Range
Therapeutic Range:
5-20 µg/mL
Toxic: > 40 µg/mL- Methodology
Gas Chromatography
Clinical Significance
Detect use. Evaluate therapeutic effect or possible toxicity.
Meprobamate (Equanil, Miltown) is the prototype of the medicinal carbamates, having been synthesized in 1950 and introduced in 1955 for clinical usage. It is employed as a sedative, antianxiety agent, and muscle relaxant and is available or oral administration in doses of 200-400 mg, alone or in combination with other drugs. As much as 2400 mg may be consumed in a single day. Side-effects of meprobamate usage include drowsiness, headache, dizziness, nausea, and paradoxical excitement. Several cases of severe hypotension and one case of fatal aplastic anemia have also been reported.