NICKEL, SERUM
- Code
- 000.0000
- Name
- NICKEL, SERUM
- Category
- None
- Department
- Send-Out
- Start Date
- Expiration Date
- Synonyms
- Ni
- CPT Codes
- 83885
- Site
- SBMF
- Reference Test
- 44523
Specimen Information
- Type
Dark blue (royal) top tube (trace element-free - serum) provided in SBMF “Trace Metal Collection Kit” (order SBMF stock #7208)
***IMPORTANT: Do not use dark blue (royal) top (EDTA) tube***- Volume
2.0 ml
- Transport Info
Clot 30 minutes
Promptly centrifuge 15 minutes
"Pour off" serum into metal-free plastic vial provided in SBMF "Trace Metal Collection Kit"
Do not use pipettes or wooden sticks to aid in specimen transfer
Refrigerated- Fasting Required?
- False
- Patient Instructions
- Reference Range
Less than or equal to 10.0 µg/L
- Methodology
Quantitative Inductively Coupled Plasma/Mass Spectrometry (ICP/MS)
Clinical Significance
Detect exposure. Evaluate toxicity.
The most frequent cause of nickel toxicity is industrial exposure. Acute exposure symptoms include headache, vertigo, nausea, vomiting, insomnia, irritability, and pulmonary symptoms similar to viral pneumonia. Effects of chronic exposure include rhinitis, sinusitis, nasal septal perforations, and asthma. Nickel refinery workers have also been reported to be at increased risk for lung and nasal cancer. Dermal exposure to soluble nickel compounds may cause vesicular eczema in hypersensitive individuals.