NICKEL, SERUM

Code
000.0000
Name
NICKEL, SERUM
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
Ni
CPT Codes
83885
Site
SBMF
Reference Test
44523
ATLAS Test Code

Specimen Information

Type

Dark blue (royal) top tube (trace element-free - serum) provided in SBMF “Trace Metal Collection Kit” (order SBMF stock #7208)
***IMPORTANT: Do not use dark blue (royal) top (EDTA) tube***

Volume

2.0 ml

Transport Info

Clot 30 minutes
Promptly centrifuge 15 minutes
"Pour off" serum into metal-free plastic vial provided in SBMF "Trace Metal Collection Kit"
Do not use pipettes or wooden sticks to aid in specimen transfer
Refrigerated

Fasting Required?
False
Patient Instructions

Reference Range

Less than or equal to 10.0 µg/L

Methodology

Quantitative Inductively Coupled Plasma/Mass Spectrometry (ICP/MS)

Clinical Significance

Detect exposure. Evaluate toxicity.

The most frequent cause of nickel toxicity is industrial exposure. Acute exposure symptoms include headache, vertigo, nausea, vomiting, insomnia, irritability, and pulmonary symptoms similar to viral pneumonia. Effects of chronic exposure include rhinitis, sinusitis, nasal septal perforations, and asthma. Nickel refinery workers have also been reported to be at increased risk for lung and nasal cancer. Dermal exposure to soluble nickel compounds may cause vesicular eczema in hypersensitive individuals.

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