PLATELET AB, DIRECT (BOUND)

Code
900.3500
Name
PLATELET AB, DIRECT (BOUND)
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
Direct Platelet Antibodies
CPT Codes
86023 X2
Site
SBMF
Reference Test
44007
ATLAS Test Code

Specimen Information

Type

(Three) Lavender, EDTA Whole Blood specimens

Volume

10.0 ml

Transport Info

CRITICAL ROOM TEMPERATURE
Samples must be received at ARUP and analyzed within 48 hours of collection
Room Temp

Fasting Required?
False
Patient Instructions

Draw Mon-Wed afternoon PREFERABLY.

NOTE: If drawn on Thursday, MUST be received at SBLHS by 4:00pm.

Do not centrifuge, Do not refrigerate, Do not remove plasma from cells.

Reference Range

IgG: Negative
IgM: Negative

Methodology

Qualitative Flow Cytometry

Clinical Significance

Detection of platelet-associated IgG and/or IgM may be used to separate thrombocytopenia of immune origin from nonimmune origin. Most patients with ITP have abnormally high levels of IgG associated with their platelets. Occasionally patients will have normal IgG levels but abnormally high levels of IgM. Dual staining and flow cytometric analysis ensures that only platelets are analyzed and relatively small volumes of blood are required. This assay does not distinguish between autoantibodies and alloantibodies, nor does it identify specific types of antiplatelet antibodies, such as those against HPA-1a. Refer to Platelet Antibodies, Indirect (44477).

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