PORPHYRINS, TOTAL, SERUM

Code
000.0000
Name
PORPHYRINS, TOTAL, SERUM
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
CPT Codes
84311
Site
SBMF
Reference Test
44077
ATLAS Test Code

Specimen Information

Type

Red, Plain

Volume

2.0 ml

Transport Info

CRITICAL - Protect from light during collection, storage, and shipment
Centrifuge and immediately transfer serum to separate light protected or foil wrapped plastic tube
Frozen

Fasting Required?
False
Patient Instructions

Reference Range

0-15 nmol/L

Methodology

Scanning Fluorometry

Clinical Significance

Useful for evaluation of cutaneous photosensitivity to rule out porphyrin disorders, particularly erythropoietic protoporphyria. The best specimen for evaluation of suspected porphyria cutanea tarda (PCT) is a urine specimen. Continued monitoring of PCT with serum is an acceptable practice. Evaluation of neurologic and/or psychiatric symptoms associated with suspected acute porphyria (such as acute intermittent porphyria) requires Porphobilinogen (PBG), Urine (23231 or 23232).

Protoporphyrin is extremely light sensitive, whereas uroporphyrin and coproporphyrin are much less so. Specimens from patients with suspected erythropoietic protoporphyria should be carefully protected from exposure to light.

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