- Start Date
- Expiration Date
- CPT Codes
- Reference Test
- Transport Info
Centrifuge and immediately transfer serum to separate plastic tube
- Fasting Required?
- Patient Instructions
- Reference Range
Indicator of protein-calorie malnutrition
Aids in assessment of total parenteral nutrition replacement
Prealbumin, also known as transthyretin, is a tryptophan-rich protein that is synthesized in hepatocytes. Its function is to bind and transport low molecular weight retinol-binding proteins. Hepatocellular synthesis insufficiencies caused by acute liver damage or dietary protein deficiency elicit a very rapid decrease in serum prealbumin concentration. Due to its short half-life in vivo (approximately two days), prealbumin is an effective nutritional marker. Prealbumin is also a negative acute phase reactant. Its level decreases in inflammation, malignancy, cirrhosis of the liver, and protein-wasting diseases of the gut or kidney.