PREALBUMIN

Code
900.3590
Name
PREALBUMIN
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
Transthyretin
CPT Codes
84134
Site
SBMF
Reference Test
29175
ATLAS Test Code

Specimen Information

Type

Gold, SST

Volume

1.0 ml

Transport Info

Centrifuge and immediately transfer serum to separate plastic tube
Frozen

Fasting Required?
False
Patient Instructions

Reference Range

20-40 mg/dL

Methodology

Immunoturbidimetric Assay

Clinical Significance

Indicator of protein-calorie malnutrition
Aids in assessment of total parenteral nutrition replacement
Prealbumin, also known as transthyretin, is a tryptophan-rich protein that is synthesized in hepatocytes. Its function is to bind and transport low molecular weight retinol-binding proteins. Hepatocellular synthesis insufficiencies caused by acute liver damage or dietary protein deficiency elicit a very rapid decrease in serum prealbumin concentration. Due to its short half-life in vivo (approximately two days), prealbumin is an effective nutritional marker. Prealbumin is also a negative acute phase reactant. Its level decreases in inflammation, malignancy, cirrhosis of the liver, and protein-wasting diseases of the gut or kidney.

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