SALICYLATE (ASPIRIN)

Code
600.4800
Name
SALICYLATE (ASPIRIN)
Category
None
Department
Chemistry
Start Date
Expiration Date
Synonyms
Aspirin; Acetylsalicylic Acid; ASA; Salicylic Acid
CPT Codes
80196
Site
Main Lab
Reference Test
ATLAS Test Code

Specimen Information

Type

Gold, SST

Volume

2.0 ml

Transport Info

Refrigerated
2 week stability

Fasting Required?
False
Patient Instructions

Reference Range

See Report

Methodology

Enzymatic

Clinical Significance

Detect use. Evaluate therapeutic effect or possible toxicity of salicylate ingestion.

Aspirin (acetylsalicylic acid or salicylate) has analgesic, antipyretic, and anti-inflammatory properties. Because of these therapeutic benefits and the general lack of serious side effects at normal doses, salicylate as aspirin is widely available.Aspirin interferes with platelet aggregation and thus prolongs the bleeding time. Due to this platelet inhibitory activity, low-dose aspirin has been recommended as prophylactic therapy for some people at risk for thromboembolic disease.There is also an epidemiological association between aspirin ingestion and Reye’s syndrome in children and adolescents with viral infections) e.g., varicella and influenza). Aspirin use is therefore contra-indicated in these patients.The symptoms of salicylate intoxication include tinnitus, diaphoresis, hyperthermia, hyperventilation, nausea, vomiting, and acid-base disturbances. CNS effects include lethargy, disorientation, and, in severe cases, coma and seizures.

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