SELENIUM BLOOD

Code
900.3925
Name
SELENIUM BLOOD
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
SELENIUM, SERUM
CPT Codes
84255
Site
SBMF
Reference Test
44051
ATLAS Test Code

Specimen Information

Type

SPECIAL INSTRUCTIONS, CALL LAB

Volume

Transport Info

Fasting Required?
False
Patient Instructions

Reference Range

23-190 µg/L

Methodology

Quantitative Inductively Coupled Plasma/Mass Spectrometry (ICP/MS)

Clinical Significance

In regions where the diet contains adequate selenium, those at risk of selenium deficiency are primarily children, dialysis patients, and others on synthetic diets deficient in selenium. Selenium is an essential constituent of glutathione peroxidase and deficiencies have been linked to increased risk of cancer. Evidence is increasing that selenium is essential for normal thyroid metabolism. In 1994, a report was published claiming a link between selenium and HIV, wherein selenium depletion increases the rate of virus replication and speeds the development of full-blown AIDS in infected individuals (Taylor EW, et al., J Med Chem 1994; 37:2637-54). Selenium toxicity is usually only of concern in acute overdose. It is associated with hair and nail loss, dermatitis, tooth decay, and neurological symptoms.

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