STONE ANALYSIS (CALCULI)

Code
900.0825
Name
STONE ANALYSIS (CALCULI)
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
Kidney stone
CPT Codes
82365
Site
SBMF
Reference Test
23000
ATLAS Test Code

Specimen Information

Type

Stone (sterile container)

Volume

Transport Info

Room Temperature

Fasting Required?
False
Patient Instructions

Reference Range

See report

Methodology

Fourier Transform Infrared Spectroscopy (FTIR)

Clinical Significance

Determination of chemical composition of kidney stones to support therapy for the causative condition

Urinary calculi have been recognized since the time of the ancient Egyptians when Hippocrates wrote in his famous oath advising the medical profession against the practice of cutting for stone. It was not until the early 19th century that the varying chemical composition of calculi was recognized. Although various treatments were postulated it was not until the 1950’s that the usefulness of information regarding the chemical composition of calculi was understood and more effective treatment could be fully utilized.From a 1979 survey, the incidence of renal calculi in the upper-Midwest was found to be 36 per 100,000 population in women and 124 per 100,000 in men. This is an extremely costly malady and accounts for approximately 1 of every 1000 hospitalizations in the United States. In addition, the risk of recurrence is estimated to be 50% within five years and 66% within nine years.The exact reasons for formation of calculi are not well understood. This is a complex process involving super-saturation of urine, the point at which a chemical can no longer stay in solution and begins to crystallize, and crystal growth inhibitors, components that will stop crystal from forming. There are many factors that will affect the point at which super-saturation occurs and how effective inhibitors are at retarding crystal growth. Some of these factors include urine volume, ion concentration, type of ions present, urine pH and types of inhibitors present.

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