STRIATED MUSCLE IGG ANTIBODY WITH REFLEX TO TITER
- STRIATED MUSCLE IGG ANTIBODY WITH REFLEX TO TITER
- Start Date
- Expiration Date
- Skeletal Muscle IgG Ab
- CPT Codes
- 86255; If reflexed, add: 86256
- Reference Test
- ATLAS Test Code
- Transport Info
Centrifuge and immediately transfer serum to separate plastic tube
- Fasting Required?
- Patient Instructions
- Reference Range
Screen: < 1:40 No antibody detected.
Titer: < 1:40 No antibody detected.
Semi-Quantitative Indirect Fluorescent Antibody (IFA)
Demonstration of striated muscle antibody may be of use in the serologic assessment of certain muscular diseases.
The presence of a skeletal muscle antibody (>/=1:80) in conjunction with a positive acetylcholine receptor site assay is helpful in the confirmatory diagnosis of myasthenia gravis (MG), especially in patients with MG and thymoma. The absence of this antibody argues against the presence of thymoma in patients with MG. Similar antibodies can be found to cardiac muscle. Patients with rheumatic fever, myocardial infarction, and a variety of postcardiotomy states may demonstrate antibodies detected using both skeletal and cardiac tissue.