RBC FOLATE

Code
900.1650
Name
RBC FOLATE
Category
None
Department
Send-Out
Start Date
Expiration Date
Synonyms
Folic Acid, RBC
CPT Codes
82747
Site
SBMF
Reference Test
30036
ATLAS Test Code

Specimen Information

Type

Lavender, EDTA, WHOLE BLOOD

Volume

1.0 ml

Transport Info

Wrap tube in foil to protect sample from light exposure
Refrigerate specimen

Fasting Required?
False
Patient Instructions

Reference Range

280-791 ng/mL

Methodology

Electrochemiluminescent Immunoassay (ECLIA)

Clinical Significance

Detect folate deficiency. Monitor therapy with folate. Evaluate megaloblastic and macrocytic anemia.
Folate has become a generic term for the miscellaneous analogues of pteroylglutamic acid (PGA). Folate is obtained from dietary sources, absorbed from the small intestine and stored in the liver. Low folate intake, malabsorption, chronic alcoholism, pregnancy and drugs such as phenytoin are causes of folate deficiency.Folate and Vitamin B12 deficiency impair DNA synthesis, resulting in abnormal maturation of red blood cells. These deficiencies are characterized by macrocytic anemia. Appropriate treatment depends on the differential diagnosis of the deficiency. Serum folate measurement provides an early index of folate status. Folate is more concentrated in red blood cells than in serum, and more closely reflects tissue stores.

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